A unique genetic test that can predict the age of increased risk of the beginning of the manifestation of the disease will help determine the likelihood of Alzheimer’s disease. The test is based on an analysis based on the study of 31 of the genetic marker. In the process of research, more than 70 thousand patients were checked, among whom were people with Alzheimer’s disease and healthy pensioners.
According to the test results, if the probability of the disease is determined at 10 and above percent, then Alzheimer’s disease manifests itself at the age of 84. For patients with a lower probability, the age of the risk of the disease begins at 95 years.
The development of Alzheimer’s disease is directly related to hereditary factors, the genetics of the patient. In particular, APOE protein, whose modifications are able to stimulate the development of the disease 12 times and inhibit the course of the disease by 40 percent plays a large role in the development of the disease.
The emergence of data on new studies using a genetic dough allows you to expand the analysis area and use not only APOE protein, but also other components when diagnosing. At the same time, genetics suggested that even if each genetic variation has a minimal effect on the course of the disease, their comprehensive, joint exposure can intensify repeatedly.
There is an opinion in the scientific environment that in order to effectively fight the progression of Alzheimer, APOE protein should be removed from the brain from the brain. And such a statement has the right to exist – experiments on mice showed that after removing APOE, experimental animals retained memory and ability to teach. At the same time, another group of scientists managed to create a drug acting on apolipoprotein E (APOE), in their opinion, the effect of medication will suspend the development of the disease.